<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Wunder DM</dc:creator>
  <dc:creator>Guibourdenche J</dc:creator>
  <dc:creator>Birkhäuser MH</dc:creator>
  <dc:creator>Bersinger NA</dc:creator>
  <dc:date>2008</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">OBJECTIVE
To evaluate anti-Müllerian hormone (AMH) as a marker of reproductive outcome after IVF/intracytoplasmic sperm injection (ICSI).


DESIGN
Longitudinal study.


SETTING
University hospital.


PATIENT(S)
Two hundred seventy-six consecutive women undergoing IVF/ICSI.


INTERVENTION(S)
Ovarian stimulation, oocyte retrieval, IVF, ICSI, embryo transfer, AMH, and inhibin B determinations in serum and follicular fluid (FF).


MAIN OUTCOME MEASURE(S)
The AMH and inhibin B concentrations in 276 matched FF/serum pairs have been determined. Different outcome groups have been compared and set in relation to the oocyte count, morphological parameters, and steroid hormone levels.


RESULT(S)
The concentrations of AMH and inhibin B in both serum and FF were significantly higher in the group of women who became pregnant in the corresponding treatment cycle than in those who did not conceive. Positive correlations were observed between serum inhibin B concentrations and embryo morphology (r = 0.126, 95% confidence interval 0.026-0.284). Serum and FF AMH or inhibin B correlated positively with the oocyte count and negatively with the pretreatment cycle day 3 FSH level and the total administered gonadotropin dose.


CONCLUSION(S)
The AMH and inhibin B levels on the day of oocyte retrieval are correlated to reproductive outcome.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/1040</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.fertnstert.2007.10.078</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/18291376</dc:relation>
  <dc:source>Fertility and sterility. - 2008</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Anti-Mullerian Hormone</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Biomarkers</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Embryo Implantation</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Embryo Transfer</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Estradiol</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Fertilization in Vitro</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Follicle Stimulating Hormone, Human</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Follicular Fluid</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Infertility</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Inhibins</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Longitudinal Studies</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Oocyte Retrieval</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Ovulation Induction</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Predictive Value of Tests</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Pregnancy</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Pregnancy Rate</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Progesterone</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Sperm Injections, Intracytoplasmic</dc:subject>
  <dc:subject xmlns:ns22="xml" ns22:lang="en">Treatment Outcome</dc:subject>
  <dc:title xmlns:ns23="xml" ns23:lang="en">Anti-Müllerian hormone and inhibin B as predictors of pregnancy after treatment by in vitro fertilization/intracytoplasmic sperm injection.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>