Beldi G Bissat A Eugster T Gürke L Stierli P Huber AR 2002 Thrombus formation in the thoracic and abdominal aorta without evidence of arteriosclerotic disease is very uncommon. We present a case of a 50-year-old woman with a mural thrombus of the upper abdominal aorta associated with a combination of two mutations predisposing for thrombophilia. The genetic analysis showed a homozygous mutation of plasminogen activator inhibitor type 1 (PAI-1)-675 (4G) and a heterozygous mutation of GP Ia 807C/T. To our knowledge, this is the first report of the combination of both mutations occurring in a patient with isolated thrombus formation of the aorta. https://sonar.ch/global/documents/1122 eng info:eu-repo/semantics/altIdentifier/doi/10.1067/mva.2002.126549 info:eu-repo/semantics/altIdentifier/pmid/12218992 Journal of vascular surgery. - 2002 Aorta, Abdominal Aortic Diseases Female Genetic Predisposition to Disease Genotype Heart Diseases Heterozygote Homozygote Humans Middle Aged Mutation Plasminogen Activator Inhibitor 1 Platelet Membrane Glycoproteins Radiography Thrombosis Mural thrombus of the aorta in association with homozygous plasminogen activator inhibitor type 1 (PAI-1)-675(4G) and heterozygous GP Ia 807C/T genotypes. http://purl.org/coar/resource_type/c_6501