<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Tahi F</dc:creator>
  <dc:creator>Du T Tran V</dc:creator>
  <dc:creator>Boucheham A</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The secondary structure of an RNA molecule represents the base-pairing interactions within the molecule and fundamentally determines its overall structure. In this chapter, we overview the main approaches and existing tools for predicting RNA secondary structures, as well as methods for identifying noncoding RNAs from genomic sequences or RNA sequencing data. We then focus on the identification of a well-known class of small noncoding RNAs, namely microRNAs, which play very important roles in many biological processes through regulating post-transcriptionally the expression of genes and which dysregulation has been shown to be involved in several human diseases.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/112458</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1007/978-1-4939-6716-2_7</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/28349425</dc:relation>
  <dc:source>Methods in molecular biology (Clifton, N.J.). - 2017</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Integrative approach</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">MicroRNA</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Noncoding RNA</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Pseudoknots</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">RNA identification</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">RNA secondary structure</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">RNA secondary structure prediction</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Computational Biology</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Computer Simulation</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Models, Molecular</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Nucleic Acid Conformation</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">RNA</dc:subject>
  <dc:title xmlns:ns15="xml" ns15:lang="en">In Silico Prediction of RNA Secondary Structure.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
