<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kofler T</dc:creator>
  <dc:creator>Daikeler T</dc:creator>
  <dc:creator>Savic Prince S</dc:creator>
  <dc:creator>Holzmann Y</dc:creator>
  <dc:creator>Bremerich J</dc:creator>
  <dc:creator>Tamm M</dc:creator>
  <dc:creator>Jahn K</dc:creator>
  <dc:date>2018</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">A 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis. After initially finding nothing suspicious, a spiro-ergometry was performed. Interestingly, we saw a relevant limitation of the inspiratory flow-volume curve under maximal exercise load. Further evaluation (in particular the bronchoscopy and the resulting biopsies) led us to the final diagnosis of a granulomatosis with polyangiitis. After 4 weeks of an established therapy regime with prednisone and rituximab the prior detected subglottic stenosis and the inspiratory flow-volume curve limitation could no longer detected. We describe a rare differential diagnosis of an exercise-induced asthma and we underline the importance of a multimodal therapy concept. We highlight the critical nature of the flow-volume curve in spiro-ergometry under maximal exercise load. We recommend frequent follow-up control visits to monitor the subglottic stenosis.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/130296</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.rmcr.2018.05.015</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/29977782</dc:relation>
  <dc:source>Respiratory medicine case reports. - 2018</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Asthma</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Exercise induced</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">GPA</dc:subject>
  <dc:title xmlns:ns4="xml" ns4:lang="en">"Exercise induced asthma" is not always asthma.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
