Hoppe S Mainzer JD Frauchiger L Ballmer PM Hess R Zumstein MA 2012 BACKGROUND AND PURPOSE Computer navigation in total knee arthroplasty is somewhat controversial. We have previously shown that femoral component positioning is more accurate with computed navigation than with conventional implantation techniques, but the clinical impact of this is unknown. We now report the 5-year outcome of our previously reported 2-year outcome study. METHODS 78 of initially 84 patients (80 of 86 knees) were clinically and radiographically reassessed 5 (5.1-5.9) years after conventional, image-based, and image-free total knee arthroplasty. The methodology was identical to that used preoperatively and at 2 years, including the Knee Society score (KSS) and the functional score (FS), and AP and true lateral standard radiographs. RESULTS Although a more accurate femoral component positioning in the navigated groups was obtained, clinical outcome, number of reoperations, KSS, FS, and range of motion were similar between the groups. INTERPRETATION The increased costs and time for navigated techniques did not translate into better functional and subjective medium-term outcome compared to conventional techniques. https://sonar.ch/global/documents/138815 eng info:eu-repo/semantics/altIdentifier/doi/10.3109/17453674.2012.747923 info:eu-repo/semantics/altIdentifier/pmid/23140107 Acta orthopaedica. - 2012 Aged Arthroplasty, Replacement, Knee Bone Malalignment Female Follow-Up Studies Humans Knee Prosthesis Male Middle Aged Minimally Invasive Surgical Procedures Monitoring, Intraoperative Osteoarthritis, Knee Pain Measurement Postoperative Care Prosthesis Design Prosthesis Failure Prosthesis Fitting Range of Motion, Articular Reference Values Reoperation Risk Assessment Surgery, Computer-Assisted Time Factors Tomography, X-Ray Computed Treatment Outcome More accurate component alignment in navigated total knee arthroplasty has no clinical benefit at 5-year follow-up. http://purl.org/coar/resource_type/c_6501