<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Goddard JP</dc:creator>
  <dc:creator>Reymond JL</dc:creator>
  <dc:date>2004</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Assaying enzyme-catalyzed transformations in high-throughput is crucial to enzyme discovery, enzyme engineering and the drug discovery process. In enzyme assays, catalytic activity is detected using labelled substrates or indirect sensor systems that produce a detectable spectroscopic signal upon reaction. Recent advances in the development of high-throughput enzyme assays have identified new labels and chromophores to detect a wide range of enzymes activities. Enzyme activity profiling and fingerprinting have also been used as tools for identification and classification, while microarray formats have been devised to increase throughput.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/143815</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.copbio.2004.06.008</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/15358001</dc:relation>
  <dc:source>Current opinion in biotechnology. - 2004</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Catalysis</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Enzyme-Linked Immunosorbent Assay</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Enzymes</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Fluorescence Resonance Energy Transfer</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Gene Expression Profiling</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Mass Spectrometry</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Oligonucleotide Array Sequence Analysis</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Peptide Mapping</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Spectrometry, Fluorescence</dc:subject>
  <dc:title xmlns:ns10="xml" ns10:lang="en">Enzyme assays for high-throughput screening.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
