Schibler U Brown SA 2005 The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study Ishida et al., 2005 [this issue of Cell Metabolism) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway. https://sonar.ch/global/documents/147097 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cmet.2005.10.001 info:eu-repo/semantics/altIdentifier/pmid/16271527 Cell metabolism. - 2005 Adrenal Glands Animals Cell Cycle Proteins Circadian Rhythm Corticotropin-Releasing Hormone Glucocorticoids Humans Light MAP Kinase Signaling System Nuclear Proteins Period Circadian Proteins Suprachiasmatic Nucleus Sympathetic Nervous System Enlightening the adrenal gland. http://purl.org/coar/resource_type/c_6501