Fassbind P Jeker B Mueller BU Bacher U Zimmerli S Endrich O Gahl B Novak U Pabst T 2019 Induction chemotherapy in AML patients may have life-threatening side effects requiring intensive care unit (ICU) treatment. We analyzed all AML patients receiving intensive chemotherapy at a single academic center between 01/2006-12/2016. At least one ICU admission was observed in 32% (76/240) patients, and 33% of those died following ICU admission. Whereas the ICU admission proportion remained stable, mortality after ICU admission decreased from 14% (2006-2008) to 3% (2014-2016; p = .056). The number of failing organ systems inversely correlated with surviving ICU admission (p < .001). Sepsis and renal, cardiac and pulmonary failure were each associated with higher mortality. With increasing ICU duration, survival probability decreased (p < .001), but remained >50% even after 14 days of ICU treatment. Progression-free and overall survival were comparable between ICU surviving patients and patients never needing ICU support. In conclusion, outcome after ICU admission of AML patients has substantially improved in recent years. application/pdf https://sonar.ch/global/documents/158 eng info:eu-repo/semantics/altIdentifier/doi/10.1080/10428194.2019.1594213 info:eu-repo/semantics/altIdentifier/pmid/30943056 info:eu-repo/semantics/openAccess Leukemia & lymphoma. - 2019 AML ICU intensive care intensive treatment outcome prognosis survival Adult Aged Critical Care Female Hospital Mortality Humans Intensive Care Units Kaplan-Meier Estimate Length of Stay Leukemia, Myeloid, Acute Male Middle Aged Patient Admission Prognosis Proportional Hazards Models Retrospective Studies Risk Factors Improved survival rates of AML patients following admission to the intensive care unit. http://purl.org/coar/resource_type/c_6501