<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Ren W</dc:creator>
  <dc:creator>Wang Q</dc:creator>
  <dc:creator>Zhu J</dc:creator>
  <dc:date>2014</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">A total synthesis of aspidophylline A, a pentacyclic akuammiline-type monoterpene indole alkaloid, is described. The synthesis features: 1) rapid access to a fully functionalized dihydrocarbazole through the desymmetrization of readily available 2-allyl-2-(o-nitrophenyl)cyclohexane-1,3-dione; 2) an intramolecular azidoalkoxylation of an enecarbamate to install both the furoindoline ring and the azido functionality; and 3) an intramolecular Michael addition for the construction of the 2-azabicyclo[3.3.1]nonane ring system.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/16165</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1002/anie.201310929</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/24452861</dc:relation>
  <dc:source>Angewandte Chemie (International ed. in English). - 2014</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">bridged ring systems</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">intramolecular Michael addition</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">monoterpene indole alkaloids</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">quaternary carbon atoms</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">total synthesis</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Heterocyclic Compounds, 4 or More Rings</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Stereoisomerism</dc:subject>
  <dc:title xmlns:ns8="xml" ns8:lang="en">Total synthesis of (±)-aspidophylline A.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>