<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Hiblot J</dc:creator>
  <dc:creator>Yu Q</dc:creator>
  <dc:creator>Sabbadini MDB</dc:creator>
  <dc:creator>Reymond L</dc:creator>
  <dc:creator>Xue L</dc:creator>
  <dc:creator>Schena A</dc:creator>
  <dc:creator>Sallin O</dc:creator>
  <dc:creator>Hill N</dc:creator>
  <dc:creator>Griss R</dc:creator>
  <dc:creator>Johnsson K</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">We introduce luciferases whose emission maxima can be tuned to different wavelengths by chemical labeling. The luciferases are chimeras of NanoLuc with either SNAP-tag or HaloTag7. Labeling of the self-labeling tag with a fluorophore shifts the emission maximum of NanoLuc to that of the fluorophore. Luciferases with tunable colors have applications as reporter genes, for the construction of biosensors and in bioimaging.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/166497</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1002/anie.201708277</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/28941028</dc:relation>
  <dc:source>Angewandte Chemie (International ed. in English). - 2017</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">bioluminescent imaging</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">luciferase</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">self-labeling protein</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">sensors</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">therapeutic drug monitoring</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Biosensing Techniques</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Fluorescent Dyes</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Genes, Reporter</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">HeLa Cells</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Luciferases</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Luminescent Measurements</dc:subject>
  <dc:title xmlns:ns13="xml" ns13:lang="en">Luciferases with Tunable Emission Wavelengths.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>