Benz S Macchione M Verolet Q Mareda J Sakai N Matile S 2016 In this report, we introduce synthetic anion transporters that operate with chalcogen bonds. Electron-deficient dithieno[3,2-b;2',3'-d]thiophenes (DTTs) are identified as ideal to bind anions in the focal point of the σ holes on the cofacial endocyclic sulfur atoms. Anion binding in solution and anion transport across lipid bilayers are found to increase with the depth of the σ holes of the DTT anionophores. These results introduce DTTs and related architectures as a privileged motif to engineer chalcogen bonds into functional systems, complementary in scope to classics such as 2,2'-bipyrroles or 2,2'-bipyridines that operate with hydrogen bonds and lone pairs, respectively. application/pdf https://sonar.ch/global/documents/171093 eng info:eu-repo/semantics/altIdentifier/doi/10.1021/jacs.6b05779 info:eu-repo/semantics/altIdentifier/pmid/27433964 info:eu-repo/semantics/openAccess Journal of the American Chemical Society. - 2016 Colloid and Surface Chemistry Biochemistry General Chemistry Catalysis Anion Transport with Chalcogen Bonds. http://purl.org/coar/resource_type/c_6501