<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Pioletti DP</dc:creator>
  <dc:date>2010</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Biomechanics may be considered as central in the development of bone tissue engineering. The initial mechanical aspects are essential to the outcome of a functional tissue engineering approach; so are aspects of interface micromotion, bone ingrowths inside the scaffold and finally, the mechanical integrity of the scaffold during its degradation. A proposed view is presented herein on how biomechanical aspects can be synthesised and where future developments are needed. In particular, a distinction is made between the mechanical and the mechanotransductional aspects of bone tissue engineering: the former could be related to osteoconduction, while the latter may be correlated to the osteoinductive properties of the scaffold. This distinction allows biomechanicians to follow a strategy in the development of a scaffold having not only mechanical targets but also incorporating some mechanotransduction principles.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/176817</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1080/10255841003630660</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/20467959</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Computer methods in biomechanics and biomedical engineering. - 2010</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Biomechanical Phenomena</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Bone and Bones</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Models, Biological</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Tissue Engineering</dc:subject>
  <dc:title xmlns:ns6="xml" ns6:lang="en">Biomechanics in bone tissue engineering.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
