Venkataraman NV Cremmel CV Zink C Huber RP Spencer ND 2014 Surface-chemical and -morphological gradients can be extremely useful in cell-biological research as high-throughput screening tools-for example, exposing a given set of cells to many different surface conditions at once, under identical ambient conditions, in order to monitor cell behavior such as proliferation or specific gene expression. They can also be used to investigate the effects of gradients themselves on cell behavior, such as migration. A number of simple, reliable techniques for both chemical- and morphological-gradient fabrication have been developed in our laboratories and are described in detail in the following. https://sonar.ch/global/documents/180992 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/B978-0-12-416742-1.00006-8 info:eu-repo/semantics/altIdentifier/pmid/24439281 Methods in cell biology. - 2014 Cell migration Gradient fabrication High-throughput screening Hydrophilicity Hydrophobicity Morphology gradient Patterning Roughness Surface-chemical gradient Cell Culture Techniques Gene Expression High-Throughput Screening Assays Humans Surface Properties Patterning gradients. http://purl.org/coar/resource_type/c_6501