Del Prete E Lutz TA Althaus J Scharrer E 1998 Several lines of evidence indicate that fatty acid oxidation contributes to control of eating. We examined the effect of inhibitors of fatty acid oxidation (mercaptoacetate, R-3-amino-4-trimethylaminobutyric acid = emeriamine) on food intake in mice because fatty acid oxidation has been shown recently to increase the hepatic membrane potential in mouse liver, and this potential has been proposed to represent a signal for control of food intake. The effect of intraperitoneal injection of mercaptoacetate (200, 400, or 600 micromol/kg body weight) and emeriamine dihydrochloride (8.7, 17.4, 34.8, or 69.6 micromol/kg body weight) was investigated in mice fed a fat-enriched diet (18% fat). Both mercaptoacetate (400 or 600 micromol/kg) and emeriamine (34.8 or 69.6 micromol/kg) significantly increased food intake. These results suggest that fatty acid oxidation is also involved in feeding control in mice. Therefore, the pertinent mechanisms can be studied in mice. https://sonar.ch/global/documents/185684 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/s0031-9384(97)00527-1 info:eu-repo/semantics/altIdentifier/pmid/9617995 Physiology & behavior. - 1998 Animals Betaine Carnitine Dietary Fats Dose-Response Relationship, Drug Eating Enzyme Inhibitors Fatty Acids Hypoglycemic Agents Injections, Intraperitoneal Male Mice Mice, Inbred ICR Oxidation-Reduction Thioglycolates Inhibitors of fatty acid oxidation (mercaptoacetate, R-3-amino-4-trimethylaminobutyric acid) stimulate feeding in mice. http://purl.org/coar/resource_type/c_6501