Delarive J Gonvers JJ 1998 We here describe a young patient who presented with chronic Budd-Chiari syndrome. An exhaustive etiological investigation to detect a procoagulable state was negative except for factor V mutation (factor V Leiden), a factor associated with resistance to activated protein C. Factor V Leiden is known to be a common, high risk factor for thrombosis. This factor should be routinely investigated in patients with Budd-Chiari syndrome, as factor V Leiden mutation is probably the procoagulable state responsible for many cases of "idiopathic" Budd-Chiari syndrome. https://sonar.ch/global/documents/189424 eng info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1572-0241.1998.184_b.x info:eu-repo/semantics/altIdentifier/pmid/9576466 The American journal of gastroenterology. - 1998 Adult Budd-Chiari Syndrome Factor V Humans Male Mutation Budd-Chiari syndrome related to factor V Leiden mutation. http://purl.org/coar/resource_type/c_6501