Bürkle A Moreno-Villanueva M Bernhard J Blasco M Zondag G Hoeijmakers JH Toussaint O Grubeck-Loebenstein B Mocchegiani E Collino S Gonos ES Sikora E Gradinaru D Dollé M Salmon M Kristensen P Griffiths HR Libert C Grune T Breusing N Simm A Franceschi C Capri M Talbot D Caiafa P Friguet B Slagboom PE Hervonen A Hurme M Aspinall R 2015 Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation. https://sonar.ch/global/documents/190457 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.mad.2015.03.006 info:eu-repo/semantics/altIdentifier/pmid/25818235 Mechanisms of ageing and development. - 2015 Ageing biomarkers Human studies MARK-AGE Aging Biomarkers European Union Female Humans Male MARK-AGE biomarkers of ageing. http://purl.org/coar/resource_type/c_6501