<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Wagner M</dc:creator>
  <dc:creator>Bonhoeffer J</dc:creator>
  <dc:creator>Erb TO</dc:creator>
  <dc:creator>Glanzmann R</dc:creator>
  <dc:creator>Häcker FM</dc:creator>
  <dc:creator>Paulussen M</dc:creator>
  <dc:creator>Weibel D</dc:creator>
  <dc:creator>Heininger U</dc:creator>
  <dc:date>2011</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">OBJECTIVE
To prospectively assess the incidence rates and characteristics of central venous line associated bloodstream infections (CLABSI) in one institution.


METHODS
All patients with indwelling central venous catheters (CVC) between 1 April 2008 and 31 March 2009 were enrolled. The medical records of patients were reviewed and information on relevant characteristics entered into a standardised questionnaire. Central laboratory records were regularly checked for positive blood cultures in study patients.


RESULTS
There were 209 CVC for a total of 14752 CVC days in 152 patients (88 males, 58%) including neonates and patients with surgical conditions and haemato-oncological and other underlying diseases. Median age at CVC insertion was 3 months (IQR 0-56 months). Fourteen CLABSI occurred in 13 patients. Overall CLABSI incidence (per 1000 CVC days) was 0.95 (9.71 for silastic percutaneous CVC, 7.65 for other CVC, 1.97 for Broviac, 0.18 for Port-a-cath). CVC remained in place for ≤ 14 days in 109 (52%) instances, 15-90 days in 45 (22%) instances and &gt; 90 days in 55 (26%) instances. The incidence of CLABSI in these three categories was 3.36, 4.36 and 0.47, respectively. Predominating cultured organisms were coagulase-negative staphylococci (N=3), S. aureus (N=3), and Enterococcus spp. (N=3).


CONCLUSIONS
CLABSI incidence varied by type of catheter and type of patient, with the highest risk in neonates (with silastic percutaneous CVC) and by far the lowest risk for Port-a-cath CVC. Prophylactic measures to reduce CLABSI should be tailored to individual types of catheters and patient characteristics.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/205516</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1136/adc.2010.208595</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/21642273</dc:relation>
  <dc:source>Archives of disease in childhood. - 2011</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Bacteremia</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Candidemia</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Catheter-Related Infections</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Catheterization, Central Venous</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Child, Preschool</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Cross Infection</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Epidemiologic Methods</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Equipment Contamination</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Hospital Units</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Infant</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Infant, Newborn</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Male</dc:subject>
  <dc:title xmlns:ns15="xml" ns15:lang="en">Prospective study on central venous line associated bloodstream infections.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>