Prosperetti C Manconi M 2015 Restless legs syndrome (RLS)/Willis-Ekbom disease is 3-fold more prevalent in pregnant than in non-pregnant women. Symptoms are particularly strong and frequent during the third trimester of pregnancy and disappear around delivery. A pre-existing form of RLS tends to worsen during pregnancy. Women who experience RLS during pregnancy have a higher risk of symptoms in further pregnancies and of developing a primary form of RLS later in life, than women free of symptoms during pregnancy. This article reviews the literature for pregnancy-related RLS, with particular attention to its epidemiology, course, possible mechanisms, management, and the impact of symptoms. https://sonar.ch/global/documents/208845 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jsmc.2015.05.016 info:eu-repo/semantics/altIdentifier/pmid/26329442 Sleep medicine clinics. - 2015 Pregnancy Restless legs syndrome Sleep Willis-Ekbom disease Female Humans Pregnancy Pregnancy Complications Prevalence Restless Legs Syndrome Restless Legs Syndrome/Willis-Ekbom Disease and Pregnancy. http://purl.org/coar/resource_type/c_6501