Godinat A Bazhin AA Goun EA 2018 Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of BLI. https://sonar.ch/global/documents/209874 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.drudis.2018.05.022 info:eu-repo/semantics/altIdentifier/pmid/29778694 Drug discovery today. - 2018 Animals Chemistry Techniques, Synthetic Firefly Luciferin Fluorescent Dyes Genes, Reporter Humans Luciferases Luminescent Measurements Molecular Imaging Oxidation-Reduction Bioorthogonal chemistry in bioluminescence imaging. http://purl.org/coar/resource_type/c_6501