<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Münz C</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Abstract: Autophagy-related (Atg) gene-encoded proteins were originally described for their crucial role in macroautophagy, a catabolic pathway for cytoplasmic constituent degradation in lysosomes. Recently it has become clear that modules of this machinery can also be used to influence endo- and exocytosis. This mini review discusses how these alternative Atg functions support virus replication and viral antigen presentation on major histocompatibility (MHC) class I and II molecules. A better understanding of the modular use of the macroautophagy machinery might enable us to manipulate these alternative functions of Atg proteins during anti-viral therapies and to attenuate virus-induced immune pathologies.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/21458</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.3390/v9100288</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/28976939</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Viruses. - 2017</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Epstein Barr virus</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">LAP (LC3 associated phagocytosis)</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">MHC class I molecules</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">MHC class II molecules</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Varizella Zoster virus</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">coxsackie B virus</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">poliovirus</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Antigen Presentation</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Autophagy</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Enterovirus B, Human</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Exocytosis</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Herpesvirus 3, Human</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Herpesvirus 4, Human</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Histocompatibility Antigens Class I</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Histocompatibility Antigens Class II</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Poliovirus</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Viral Proteins</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Virus Activation</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Virus Replication</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Viruses</dc:subject>
  <dc:title xmlns:ns22="xml" ns22:lang="en">Autophagy Proteins in Viral Exocytosis and Anti-Viral Immune Responses.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>