Krayenbühl BH Panizzon RG 2000 Since silicone has rapidly become one of the most commonly used prosthetic materials in the last 30 years in modern medicine, we have consequently been witnessing more silicone-related disease. Especially after silicone breast implantation, defects in the breast implant have led to serious complications, whereas complications of silicone prosthesis implantation in other body parts are less frequent. Here we present an unusual clinical presentation of a silicone granuloma in a patient with a 27-year history of a wide excision of a melanoma of the right lower extremity and subsequent soft-tissue reconstruction using a silicone device. https://sonar.ch/global/documents/2223 eng info:eu-repo/semantics/altIdentifier/doi/10.1159/000018411 info:eu-repo/semantics/altIdentifier/pmid/10894978 Dermatology (Basel, Switzerland). - 2000 Electron Probe Microanalysis Female Granuloma Humans Middle Aged Silicone Elastomers Silicones Skin Diseases Sulfur Silicone granuloma. http://purl.org/coar/resource_type/c_6501