<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Jungwirth-Weinberger A</dc:creator>
  <dc:creator>Grubhofer F</dc:creator>
  <dc:creator>Imam MA</dc:creator>
  <dc:creator>Bachmann E</dc:creator>
  <dc:creator>Wirth S</dc:creator>
  <dc:date>2018</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">To avoid infections and wound healing disorders, Triclosan coated sutures have been invented. Little is known of these sutures regarding their tensile properties. Three different Triclosan coated sutures (Vicryl 1 plus, PDS 0 plus, Monocryl 3-0 plus) were tested at several time points over 42 days regarding load to failure, strain, and stiffness compared to their non-coated versions (Vicryl 1, PDS 0, Monocryl 3-0). Four different measurement points were made. Suture loops were fixed in a material testing machine over two metal bars which were moved apart creating a stress to the fiber. Unpaired, two-tailed t-test were performed for each group (untreated and treated) while level of significance was defined at a level of p &lt; 0.05. Vicryl 1 was significantly stronger on day 14 than Vicryl 1 plus (p = 0.033). On day 28, significant changes were found in PDS 0 which was weaker compared to PDS 0 plus (p = 0.039) and Vicryl 1 which was stronger than Vicryl 1 plus (p = 0.032). We have seen that Vicryl 1 plus sutures are significantly weaker according to loading to failure after 14 and 28 days, which might cause incisional hernias. PDS 0 sutures are used to reconstruct tendons, therefore a longer durableness might be of interest as re-ruptures of tendons are problematic. Our in vitro findings support, the use of Triclosan coated PDS plus sutures and Vicryl sutures as they show a longer resistance. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1777-1782, 2018.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/229053</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1002/jor.23814</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/29205483</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Journal of orthopaedic research : official publication of the Orthopaedic Research Society. - 2018</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Triclosan</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">material properties</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">orthopaedic surgery</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">suture</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Biomechanical Phenomena</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Materials Testing</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Polyglactin 910</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Surgical Wound Infection</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Sutures</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Tensile Strength</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Triclosan</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Wound Healing</dc:subject>
  <dc:title xmlns:ns13="xml" ns13:lang="en">Mechanical properties of Triclosan sutures.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
