<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Lu W</dc:creator>
  <dc:creator>Wu P</dc:creator>
  <dc:creator>Zhang Z</dc:creator>
  <dc:creator>Chen J</dc:creator>
  <dc:creator>Chen X</dc:creator>
  <dc:creator>Ewelina B</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">BACKGROUND
To date, no studies compared curative effects of thermal lesions in deep and superficial dermal layers in the same patient (face-split study).


OBJECTIVE
To evaluate skin laxity effects of microneedle fractional radiofrequency induced thermal lesions in different dermal layers.


METHODS AND MATERIALS
13 patients underwent three sessions of a randomized face-split microneedle fractional radiofrequency system (MFRS) treatment of deep dermal and superficial dermal layer. Skin laxity changes were evaluated objectively (digital images, 2 independent experts) and subjectively (patients' satisfaction numerical rating).


RESULTS
12 of 13 subjects completed a course of 3 treatments and a 1-year follow-up. Improvement of nasolabial folds in deep dermal approach was significantly better than that in superficial approach at three months (P=.0002) and 12 months (P=.0057) follow-up. Effects on infraorbital rhytides were only slightly better (P=.3531).


CONCLUSION
MFRS is an effective method to improve skin laxity. Thermal lesion approach seems to provide better outcomes when applied to deep dermal layers. It is necessary to consider the skin thickness of different facial regions when choosing the treatment depth.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/231828</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1080/14764172.2016.1256485</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/27849406</dc:relation>
  <dc:source>Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. - 2017</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Botulinum toxins</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">cosmeceuticals</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">lasers and light sources</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">mesotherapy</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">microdermabrasion</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">topical agents</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Aged</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Asian Continental Ancestry Group</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Cosmetic Techniques</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Double-Blind Method</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Face</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Middle Aged</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Patient Satisfaction</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Prospective Studies</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Radiofrequency Therapy</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Rejuvenation</dc:subject>
  <dc:subject xmlns:ns22="xml" ns22:lang="en">Skin</dc:subject>
  <dc:subject xmlns:ns23="xml" ns23:lang="en">Skin Aging</dc:subject>
  <dc:subject xmlns:ns24="xml" ns24:lang="en">Swine</dc:subject>
  <dc:title xmlns:ns25="xml" ns25:lang="en">Curative effects of microneedle fractional radiofrequency system on skin laxity in Asian patients: A prospective, double-blind, randomized, controlled face-split study.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>