Hiscock TW Tschopp P Tabin CJ 2017 Critical steps in forming the vertebrate limb include the positioning of digits and the positioning of joints within each digit. Recent studies have proposed that the iterative series of digits is established by a Turing-like mechanism generating stripes of chondrogenic domains. However, re-examination of available data suggest that digits are actually patterned as evenly spaced spots, not stripes, which then elongate into rod-shaped digit rays by incorporating new cells at their tips. Moreover, extension of the digit rays and the patterning of the joints occur simultaneously at the distal tip, implying that an integrated model is required to fully understand these processes. application/pdf https://sonar.ch/global/documents/232418 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.devcel.2017.04.021 info:eu-repo/semantics/altIdentifier/pmid/28586643 info:eu-repo/semantics/openAccess Developmental cell. - 2017 Turing mechanism digit specification joint formation Animals Body Patterning Extremities Joints Organogenesis Vertebrates On the Formation of Digits and Joints during Limb Development. http://purl.org/coar/resource_type/c_6501