<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Stienen MN</dc:creator>
  <dc:creator>Joswig H</dc:creator>
  <dc:creator>Smoll NR</dc:creator>
  <dc:creator>Corniola MV</dc:creator>
  <dc:creator>Schaller K</dc:creator>
  <dc:creator>Hildebrandt G</dc:creator>
  <dc:creator>Gautschi OP</dc:creator>
  <dc:date>2016</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">OBJECTIVE
To analyze the influence of body mass index (BMI) on subjective and objective measures of pain, functional impairment, and health-related quality of life in patients with lumbar degenerative disc disease undergoing surgery.


METHODS
Prospective institutional review board-approved 2-center study, measuring visual analog scale (VAS) back and leg pain, Roland-Morris Disability Index (RMDI), Oswestry Disability Index (ODI), EuroQol 5D questionnaire, and Short Form-12 at baseline, 6 weeks, 6 months, and 1 year postoperatively. T-scores of objective functional impairment (OFI) were determined using the Timed Up and Go (TUG) test.


RESULTS
A total of 375 patients with a median BMI of 26.6 kg/m2 (94 obese patients [BMI ≥30 kg/m2]) were included. Obese patients presented more VAS back pain (mean, 4.7 vs. 3.6; P = 0.001) and greater disability on the RMDI (mean, 12.6 vs. 11.3; P = 0.045). The prevalence and severity of OFI were similar in obese and nonobese patients. There was a weak positive correlation between BMI and VAS back pain (r = 0.1552; P = 0.0026), on both RMDI (r = 0.1138; P = 0.0276) and ODI (r = 0.1075; P = 0.0374). There was no correlation between BMI and TUG T-scores (r = 0.0475; P = 0.3585). Obese patients were as likely as nonobese patients to show a positive 6-week treatment response, and the outcome up to 1 year was similar.


CONCLUSIONS
BMI positively correlates with VAS back pain, RMDI, and ODI. Standardized TUG T scores reflect the patient's degree of OFI well, irrespective of BMI. The TUG test appears to be a good means to estimate functional impairment in populations with a high prevalence of obesity.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/232585</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.wneu.2016.09.070</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/27686509</dc:relation>
  <dc:source>World neurosurgery. - 2016</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Body mass index</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Body weight</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Degenerative disc disease</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Disability</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Health-related quality of life</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Impairment</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Obesity</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Objective functional impairment</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Pain</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Patient evaluation</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Timed Up and Go test</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Aged</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Body Mass Index</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Disability Evaluation</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Follow-Up Studies</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Intervertebral Disc Degeneration</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Intervertebral Disc Displacement</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Linear Models</dc:subject>
  <dc:subject xmlns:ns22="xml" ns22:lang="en">Lumbar Vertebrae</dc:subject>
  <dc:subject xmlns:ns23="xml" ns23:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns24="xml" ns24:lang="en">Middle Aged</dc:subject>
  <dc:subject xmlns:ns25="xml" ns25:lang="en">Pain</dc:subject>
  <dc:subject xmlns:ns26="xml" ns26:lang="en">Pain Measurement</dc:subject>
  <dc:subject xmlns:ns27="xml" ns27:lang="en">Quality of Life</dc:subject>
  <dc:subject xmlns:ns28="xml" ns28:lang="en">Severity of Illness Index</dc:subject>
  <dc:subject xmlns:ns29="xml" ns29:lang="en">Spinal Fusion</dc:subject>
  <dc:subject xmlns:ns30="xml" ns30:lang="en">Surveys and Questionnaires</dc:subject>
  <dc:subject xmlns:ns31="xml" ns31:lang="en">Switzerland</dc:subject>
  <dc:title xmlns:ns32="xml" ns32:lang="en">Influence of Body Mass Index on Subjective and Objective Measures of Pain, Functional Impairment, and Health-Related Quality of Life in Lumbar Degenerative Disc Disease.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>