Legrand T Richard V Bonnefoy-Mazure A Armand S Miozzari HH Turcot K 2020 BACKGROUND We evaluated the influence of the body-mass index (BMI) on the estimation of the static frontal knee alignment (FKA) using three-dimensional (3D) reconstruction method based on movement analysis. METHODS Two-hundred nineteen knees (120 individuals with end-stage osteoarthritis) were analyzed. The validity of the 3D method was evaluated under comparison with a reference method based on weight bearing full-leg length radiography. Extensive statistical analyses (Pearson's correlation, one-way ANOVA, linear regression, boxplot diagram) over four groups of BMI (normal, overweight, obese class I and obese classes II and III) were performed. RESULTS For BMI below 25 kg/m2, the validity of the 3D method was confirmed. For BMI over 25 kg/m2, there was an increasing error of the 3D method, especially for the obese groups affected with a large varus alignment. CONCLUSIONS In a biomechanical context of movement analysis, the results of the study suggest that the 3D method may represent a satisfying alternative to the full-leg radiograph method with limitations regarding to BMI over 25 kg/m2. application/pdf https://sonar.ch/global/documents/232815 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.knee.2019.09.020 info:eu-repo/semantics/altIdentifier/pmid/31870700 info:eu-repo/semantics/openAccess The Knee. - 2020 3D static analysis Body-mass index Frontal alignment Knee Obese Osteoarthritis Body Mass Index Humans Imaging, Three-Dimensional Knee Joint Movement Osteoarthritis, Knee Radiography Range of Motion, Articular Weight-Bearing The impact of body-mass index on the frontal knee alignment estimation using three-dimensional reconstruction based on movement analysis. http://purl.org/coar/resource_type/c_6501