Knecht PB Schmid U Romppainen T Hediger A Funk J Kanngiesser H Kniestedt C 2011 PURPOSE We present a prototype of the hand-held dynamic contour tonometer (HH-DCT) and prospectively compare this HH-DCT with the well-established Perkins applanation tonometer (PAT) and the TonoPenXL (TPXL). METHODS In a prospective, single-centre, randomized study, intraocular pressure (IOP) readings were taken in random order using HH-DCT, PAT and TPXL tonometers. Intra-observer variability was calculated for each observer and compared between three experienced ophthalmologists and an inexperienced medical student. RESULTS Ninety-two corneas of 92 healthy participants were enrolled. IOP [mean mmHg ± standard deviation (SD)] as measured by HH-DCT was 16.97 ± 2.71, by PAT 13.98 ± 2.52 and by TPXL 13.34 ± 2.68. The range of three consecutive IOP readings differed significantly between the devices [p < 0.001; mean range: 1.45 ± 1.07 (HH-DCT), 1.87 ± 0.97 (PAT) and 2.08 ± 1.77 (TPXL)]. There was no difference of the range in all devices between the ophthalmologists and the medical student (HH-DCT p = 0.68, PAT p = 0.54, TPXL p = 0.48). CONCLUSION IOP readings measured by HH-DCT are significantly higher than by PAT and TPXL. The differences of IOP measurements are in good accordance with previous studies using the slit-lamp-mounted DCT (SL-DCT) and Goldmann Applanation Tonometry, where SL-DCT readings were 1-3.2 mmHg higher. HH-DCT seems to give more constant results, which can be seen in the lower intra-observer variability compared to PAT and TPXL. application/pdf https://sonar.ch/global/documents/236037 eng info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1755-3768.2009.01625.x info:eu-repo/semantics/altIdentifier/pmid/21348963 info:eu-repo/semantics/openAccess Acta ophthalmologica. - 2011 Adult Female Humans Intraocular Pressure Male Middle Aged Observer Variation Prospective Studies Reproducibility of Results Tonometry, Ocular Young Adult Hand-held dynamic contour tonometry. http://purl.org/coar/resource_type/c_6501