<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Schmid R</dc:creator>
  <dc:creator>Studer E</dc:creator>
  <dc:creator>Hirsbrunner G</dc:creator>
  <dc:date>2020</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows. Furthermore, it should be investigated, if a third administration could prolong the effect of the cycle suppression. A total of 21 cows (more than four weeks post partum) were vaccinated twice, at least 35 days apart, with 2 ml Improvac® (0.4 mg of a GnRH-analogon) subcutaneously on one side of the neck. Over a period of 368 days and in the course of 18 farm visits these cows were examined gynecologically and re-vaccinated if they showed signs of estrus behaviour or ovarian activity. After the second vaccination the cycle of the cows was suppressed for an average period of 114 days (59-175 days) and the effect could be prolonged by a booster of the vaccine for another 127 days in three cows. Estrus behaviour was absent for a longer period than ovarian activity was. The vaccine was tolerated well: apart from slight swelling at the injection site, no side effects were observed. Our results demonstrate that two immunizations with Improvac® are an easily applicable method for the suppression of cyclic activity in cows for a mean period of 114 days. The duration of cycle suppression was prolonged by a booster of the vaccination.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/241947</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.17236/sat00245</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/32004139</dc:relation>
  <dc:source>Schweizer Archiv fur Tierheilkunde. - 2020</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Anti-GnRH</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Brunst</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Immunisierung</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Improvac®</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Rind</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">bovino</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">cattle</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">chaleurs</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">estro</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">immunisation</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">immunizzazione</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">oestrus</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">vaches</dc:subject>
  <dc:title xmlns:ns14="xml" ns14:lang="en">[Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study].</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>