<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Stampfli AR</dc:creator>
  <dc:creator>Seebeck FP</dc:creator>
  <dc:date>2020</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Sulfoxide synthases are non-heme iron enzymes that catalyze oxidative carbonsulfur bond formation in the biosynthesis of thiohistidines such as ergothioneine and ovothiol. The catalytic mechanism of these enzymes has been studied by protein crystallography, steady-state kinetics, non-natural amino acid incorporation and computational modeling. This review discusses the current status of this research and also highlights similarities between the CS bond forming activity of sulfoxide synthases with that of synthetic coordination compounds.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/242129</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cbpa.2020.06.007</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/32726707</dc:relation>
  <dc:source>Current opinion in chemical biology. - 2020</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Carbonesulfur bond formation</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Enzymology</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Ergothioneine</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Non-heme iron enzyme</dc:subject>
  <dc:title xmlns:ns5="xml" ns5:lang="en">The catalytic mechanism of sulfoxide synthases.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>