<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Nickel B</dc:creator>
  <dc:creator>Sayasone S</dc:creator>
  <dc:creator>Vonghachack Y</dc:creator>
  <dc:creator>Odermatt P</dc:creator>
  <dc:creator>Marti H</dc:creator>
  <dc:date>2015</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Northern Cambodia and Southern Laos are highly endemic for Schistosoma mekongi. However, there is currently no immunological assay available that is specific for this form of schistosomiasis. We have validated Schistosoma mansoni antigens to detect S. mekongi-directed antibodies in human sera collected from a highly S. mekongi endemic region in Laos. On two consecutive days stool samples of 234 individuals were analyzed by Kato-Katz for presence of S. mekongi eggs and the results were correlated with serology. A sensitivity of 94.5% was calculated for a combination of ELISA and indirect fluorescence assay (IFA) as compared to the detection of S. mekongi eggs in stool samples as gold standard. The results demonstrate that S. mansoni antigens can be used for the diagnosis of S. mekongi infections.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/246689</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.actatropica.2014.08.001</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/25116398</dc:relation>
  <dc:source>Acta tropica. - 2015</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">ELISA</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">IFA</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Kato-Katz</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Laos</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Schistosoma mansoni</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Schistosoma mekongi</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Serodiagnosis</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Adolescent</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Aged</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Antigens, Helminth</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Cambodia</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Child</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Child, Preschool</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Cross Reactions</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Enzyme-Linked Immunosorbent Assay</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Feces</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Fluorescent Antibody Technique, Indirect</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns22="xml" ns22:lang="en">Laos</dc:subject>
  <dc:subject xmlns:ns23="xml" ns23:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns24="xml" ns24:lang="en">Middle Aged</dc:subject>
  <dc:subject xmlns:ns25="xml" ns25:lang="en">Parasite Load</dc:subject>
  <dc:subject xmlns:ns26="xml" ns26:lang="en">Schistosoma</dc:subject>
  <dc:subject xmlns:ns27="xml" ns27:lang="en">Schistosoma mansoni</dc:subject>
  <dc:subject xmlns:ns28="xml" ns28:lang="en">Schistosomiasis</dc:subject>
  <dc:subject xmlns:ns29="xml" ns29:lang="en">Sensitivity and Specificity</dc:subject>
  <dc:subject xmlns:ns30="xml" ns30:lang="en">Young Adult</dc:subject>
  <dc:title xmlns:ns31="xml" ns31:lang="en">Schistosoma mansoni antigen detects Schistosoma mekongi infection.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>