<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Lipp HP</dc:creator>
  <dc:creator>Wolfer DP</dc:creator>
  <dc:date>1998</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Cognition in transgenic and knockout mice is preferentially assessed by spatial learning in the Morris water maze. Awareness is growing, however, that the putative cognitive deficits observed using such a paradigm may be biased by the genetic background and behavioral peculiarities of the specific animals used. Recent progress in cognitive research includes new behavioral tests and refined analysis of performance impairments. Advances in our understanding of memory and learning are being made possible through use of transgenic rescue of disrupted genes, inducible and reversible gene targeting in selected brain regions, and single-cell recordings of hippocampal place cells in mutant mice.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/264819</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/s0959-4388(98)80151-7</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/9635213</dc:relation>
  <dc:source>Current opinion in neurobiology. - 1998</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Cognition</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Maze Learning</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Mice</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Mice, Knockout</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Mice, Transgenic</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Nerve Growth Factors</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Neural Cell Adhesion Molecules</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Rats</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Signal Transduction</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Swimming</dc:subject>
  <dc:title xmlns:ns13="xml" ns13:lang="en">Genetically modified mice and cognition.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>