Herbort CP Chave JP 1998 PURPOSE To quantify the inflammatory reaction that can be seen in HIV-infected patients with cytomegalovirus (CMV) retinitis after the introduction of an HIV protease inhibitor and correlate it with ocular findings and systemic HIV parameters. METHODS Report of a patient with CMV retinitis systematically followed by slit-lamp examination, funduscopy, fundus photographs and laser flare photometry before and after introduction of an HIV protease inhibitor. RESULTS Manifest granulomatous panuveitis developed 2 months after the introduction of the protease inhibitor indinavir (CD4 rise from 2 to 64 CD4/mm3) and coincided with cicatrization of the CMV retinitis in the absence of efficient anti-CMV therapy. CONCLUSION Occurrence of uveitis in patients with CMV retinitis following the introduction of HIV protease inhibitors may be a factor indicating a good ocular prognosis, possibly pointing to the presence of the anti-CMV repertoire in the reconstituting CD4 cell population. https://sonar.ch/global/documents/277762 eng info:eu-repo/semantics/altIdentifier/doi/10.1007/s004170050161 info:eu-repo/semantics/altIdentifier/pmid/9801897 Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. - 1998 Adult CD4 Lymphocyte Count Cicatrix Cytomegalovirus Infections HIV Protease Inhibitors Humans Indinavir Male Prognosis Retinitis Treatment Outcome Uveitis Cicatrization of cytomegalovirus retinitis following introduction of highly active anti-retroviral therapy: uveitis as a possible indicator of good ocular prognosis. http://purl.org/coar/resource_type/c_6501