<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Rasoamiaranjanahary L</dc:creator>
  <dc:creator>Guilet D</dc:creator>
  <dc:creator>Marston A</dc:creator>
  <dc:creator>Randimbivololona F</dc:creator>
  <dc:creator>Hostettmann K</dc:creator>
  <dc:date>2003</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Five isopimarane diterpenes (7beta-hydroxyisopimara-8,15-dien-14-one, 14alpha-hydroxyisopimara-7,15-dien-1-one, 1beta,14alpha-dihydroxyisopimara-7,15-diene, 7beta-hydroxyisopimara-8(14),15-dien-1-one and 7beta-acetoxyisopimara-8(14),15-dien-1-one) have been isolated from the leaves of Hypoestes serpens (Acanthaceae). All compounds exhibited antifungal activity against both the plant pathogenic fungus Cladosporium cucumerinum and the yeast Candida albicans; two of them also displayed an acetylcholinesterase inhibition. The structures of the compounds were determined by means of spectrometric methods, including 1D and 2D NMR experiments and MS analysis.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/277919</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/s0031-9422(03)00154-7</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/12943772</dc:relation>
  <dc:source>Phytochemistry. - 2003</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Acanthaceae</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Antifungal Agents</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Candida albicans</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Cholinesterase Inhibitors</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Cladosporium</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Diterpenes</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Magnetic Resonance Spectroscopy</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Plant Leaves</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Spectrometry, Mass, Electrospray Ionization</dc:subject>
  <dc:title xmlns:ns10="xml" ns10:lang="en">Antifungal isopimaranes from Hypoestes serpens.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>