Villemure JG Daniel RT 2006 OBJECTS Outline the indications, investigation, surgical technique, pitfalls, complications and benefits of peri-insular hemispherotomy (PIH) in the surgical treatment of paediatric epilepsy. MATERIALS AND METHODS This report is based on a consecutive series of 43 children who underwent PIH. Sixty percent were males; there were slightly more left-sided surgeries. Median interval between seizure onset and surgery was 5 years. In more than half the cases, the anatomical substrate was congenital. There were few complications: one death, one hydrocephalus and two anatomically remote haemorrhages. Ninety percent of the patients have remained in Engel's class I epilepsy outcome. CONCLUSIONS There are clear indications for hemispherectomy in children. In some instances of incomplete deficit, timing of surgery remains a major concern. The less invasive approach to eliminate the influence of the diseased hemisphere, in our opinion, is with disconnective techniques of hemispherectomy, and among the latter, peri-insular hemispherotomy provides, in our opinion, the best complications-benefits ratio. application/pdf https://sonar.ch/global/documents/278018 eng info:eu-repo/semantics/altIdentifier/doi/10.1007/s00381-006-0134-3 info:eu-repo/semantics/altIdentifier/pmid/16804712 info:eu-repo/semantics/openAccess Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. - 2006 Adolescent Adult Cerebral Cortex Child Child, Preschool Electroencephalography Epilepsy Female Follow-Up Studies Hemispherectomy Humans Magnetic Resonance Imaging Male Pediatrics Treatment Outcome Peri-insular hemispherotomy in paediatric epilepsy. http://purl.org/coar/resource_type/c_6501