<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Multerer MD</dc:creator>
  <dc:creator>Wittwer LD</dc:creator>
  <dc:creator>Stopka A</dc:creator>
  <dc:creator>Barac D</dc:creator>
  <dc:creator>Lang C</dc:creator>
  <dc:creator>Iber D</dc:creator>
  <dc:date>2018</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modeling this process can provide novel insights into development and the principles that orchestrate the developmental processes. This chapter focuses on the mathematical description and numerical simulation of developmental processes. In particular, we discuss the mathematical representation of morphogen and tissue dynamics on static and growing domains, as well as the corresponding tissue mechanics. In addition, we give an overview of numerical methods that are routinely used to solve the resulting systems of partial differential equations. These include the finite element method and the Lattice Boltzmann method for the discretization as well as the arbitrary Lagrangian-Eulerian method and the Diffuse-Domain method to numerically treat deforming domains.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/278127</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1007/978-1-4939-8772-6_13</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/30324601</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Methods in molecular biology (Clifton, N.J.). - 2018</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">In silico morphogenesis</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Morphogen dynamics</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Tissue dynamics</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Tissue mechanics</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Algorithms</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Cell Proliferation</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Computer Simulation</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Embryonic Development</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Finite Element Analysis</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Intercellular Signaling Peptides and Proteins</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Models, Biological</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Morphogenesis</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Signal Transduction</dc:subject>
  <dc:title xmlns:ns15="xml" ns15:lang="en">Simulation of Morphogen and Tissue Dynamics.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
