Eyer MM Läng M Aujesky D Marschall J 2016 BACKGROUND Overtreatment of asymptomatic bacteriuria (ASB) is widespread and may result in antibiotic side-effects, excess costs to the healthcare system, and may potentially trigger antimicrobial resistance. According to international management guidelines, ASB is not an indication for antibiotic treatment (with few exceptions). AIM To determine reasons for using antibiotics to treat ASB in the absence of a treatment indication. METHODS A qualitative study was conducted at a tertiary care hospital in Switzerland during 2011. We interviewed 21 internal medicine residents and attending physicians selected by purposive sampling, using a semi-structured questionnaire. Responses were analysed in an inductive thematic content approach using dedicated software (MAXQDA(®)). FINDINGS In the 21 interviews, the following thematic rationales for antibiotic overtreatment of ASB were reported (in order of reporting frequency): (i) treating laboratory findings without taking the clinical picture into account (N = 17); (ii) psychological factors such as anxiety, overcautiousness, or anticipated positive impact on patient outcomes (N = 13); (iii) external pressors such as institutional culture, peer pressure, patient expectation, and excessive workload that interferes with proper decision-making (N = 9); (iv) difficulty with interpreting clinical signs and symptoms (N = 8). CONCLUSION In this qualitative study we identified both physician-centred factors (e.g. overcautiousness) and external pressors (e.g. excessive workload) as motivators for prescribing unnecessary antibiotics. Also, we interpreted the frequently cited practice of treating asymptomatic patients based on laboratory findings alone as lack of awareness of evidence-based best practices. https://sonar.ch/global/documents/278488 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jhin.2016.04.007 info:eu-repo/semantics/altIdentifier/pmid/27174231 The Journal of hospital infection. - 2016 Asymptomatic bacteriuria Overtreatment Qualitative research Urinary tract infection Anti-Bacterial Agents Asymptomatic Infections Bacteriuria Drug Prescriptions Drug Utilization Evaluation Studies as Topic Humans Interviews as Topic Medical Overuse Practice Patterns, Physicians' Surveys and Questionnaires Switzerland Tertiary Care Centers Overtreatment of asymptomatic bacteriuria: a qualitative study. http://purl.org/coar/resource_type/c_6501