Hördegen P Hertzberg H Heilmann J Langhans W Maurer V 2003 Forty-eight helminth-free lambs were divided into eight groups (A-H) of six animals. Groups A-G were infected artificially with 10,000 third stage larvae of Haemonchus contortus and 20,000 third stage larvae of Trichostrongylus colubriformis, whereas group H remained uninfected. Thirty days post-infection the lambs were treated orally with a single dosage of one of the following products: group A with 3 mg/kg body weight (BW) of an aqueous ethanol extract (70%, v/v) of the seeds of Azadirachta indica A. Juss syn. Melia azedarach L. (Meliaceae); group B with 1 g/kg BW of a raw powder of the leaves of Ananas comosus (L.) Merr. (Bromeliaceae); group C with 0.3 mg/kg BW of an aqueous ethanol extract of a 1:1 mixture (g/g) of Vernonia anthelmintica (L.) Willd. (Asteraceae) seeds and Embelia ribes Burm (Myrsinaceae) fruits; group D with 183 mg/kg BW of an aqueous ethanol extract of the whole plants of Fumaria parviflora Lam. (Fumariaceae); group E with 28 mg/kg BW of an aqueous ethanol extract of the seeds of Caesalpinia crista L. (Caesalpiniaceae); group F with 25 mg/kg BW of pyrantel tartrate and group G with 50% ethanol. Group H remained untreated. Only the ethanol extract of F. parviflora caused a strong reduction of the faecal egg counts (100%) and a 78.2 and 88.8% reduction of adult H. contortus and T. colubriformis on day 13 post-treatment. The extract was as effective as the reference compound pyrantel tartrate. Therefore, the ethanol extract itself or single constituents of F. parviflora could be a promising alternative source of anthelmintic for the treatment of gastrointestinal trichostrongylids in small ruminants. https://sonar.ch/global/documents/279019 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetpar.2003.07.027 info:eu-repo/semantics/altIdentifier/pmid/14597279 Veterinary parasitology. - 2003 Administration, Oral Animals Anthelmintics Feces Female Haemonchiasis Haemonchus Intestinal Diseases, Parasitic Male Parasite Egg Count Phytotherapy Plant Extracts Random Allocation Sheep Sheep Diseases Trichostrongylosis Trichostrongylus The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs. http://purl.org/coar/resource_type/c_6501