<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Barzanò G</dc:creator>
  <dc:creator>Cheseaux A</dc:creator>
  <dc:creator>Hu X</dc:creator>
  <dc:date>2019</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Z-Selective synthesis of vinyl boronates is challenging. This work describes Fe-catalyzed addition of alkyl radicals, formed by the corresponding alkyl halides, to ethynyl ethynylboronic acid pinacol ester that gives rise to Z-vinyl boronates in high stereoselectivity. The method works best for tertiary and secondary alkyl iodides. The Z-vinyl boronate products are easily converted to other Z-alkenes by transformation of the boronate group. The method is applied for the formal total synthesis of a 5-HT2c receptor agonist.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/282408</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.orglett.8b03772</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/30624069</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Organic letters. - 2019</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Physical and Theoretical Chemistry</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Organic Chemistry</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Biochemistry</dc:subject>
  <dc:title xmlns:ns4="xml" ns4:lang="en">Z-Selective Synthesis of Vinyl Boronates through Fe-Catalyzed Alkyl Radical Addition.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>