<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Makek MS</dc:creator>
  <dc:creator>Andrews JC</dc:creator>
  <dc:creator>Fisch U</dc:creator>
  <dc:date>1989</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The malignant transformation of a nasopharyngeal angiofibroma is a rare occurrence. This report describes the development of a fibrosarcoma in a patient over a 20-year period after four surgical procedures and two courses of radiation therapy to control a nasopharyngeal angiofibroma. A review of the literature revealed similar descriptions of this problem. Radiation likely plays a major role in causing the malignant change. An initial complete surgical excision can prevent recurrence of a nasopharyngeal angiofibroma as well as sarcomatous transformation. With the availability of surgical procedures that can completely and safely resect almost all nasopharyngeal angiofibromas, radiation therapy can be avoided.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/286917</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1288/00005537-198210000-00021</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/2552239</dc:relation>
  <dc:source>The Laryngoscope. - 1989</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Adolescent</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Combined Modality Therapy</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Fibrosarcoma</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Histiocytoma, Benign Fibrous</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Nasopharyngeal Neoplasms</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Nasopharynx</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Neoplasm Recurrence, Local</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Radiotherapy</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Time Factors</dc:subject>
  <dc:title xmlns:ns12="xml" ns12:lang="en">Malignant transformation of a nasopharyngeal angiofibroma.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>