Held W Coudert JD Zimmer J 2003 The identification of NK cell receptors specific for MHC class I molecules has greatly improved our knowledge of NK cell reactivity and specificity. Inhibitory receptors prevent NK cell activation directed against cells expressing self-MHC class I molecules. Consequently, diseased cells that do not express self-MHC class I molecules become susceptible to NK cell-mediated attack. Because of the specificity and distribution of inhibitory NK cell receptors, cells that express non-self (allogeneic) MHC class I molecules are also susceptible to NK cell reactions. This feature has been exploited in a clinical setting to treat leukemia patients. https://sonar.ch/global/documents/289348 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/s0952-7915(02)00031-6 info:eu-repo/semantics/altIdentifier/pmid/12633675 Current opinion in immunology. - 2003 Adaptation, Physiological Animals Histocompatibility Antigens Class I Humans Killer Cells, Natural Lymphocyte Activation Receptors, Immunologic The NK cell receptor repertoire: formation, adaptation and exploitation. http://purl.org/coar/resource_type/c_6501