Kostner L Anzengruber F Guillod C Recher M Schmid-Grendelmeier P Navarini AA 2017 Allergic contact dermatitis (ACD) is a common skin disease caused by a T cell-mediated immune reaction to usually innocuous allergens. ACD can have grave medical and socioeconomic consequences. ACD and irritant contact dermatitis often occur together. A detailed history and clinical examination are crucial and guide patch testing, which is the gold standard to diagnose ACD. T-cell clones persisting in the skin may explain the tendency of ACD to relapse even after years of allergen avoidance. Traditional treatments for ACD are topical steroids, calcineurin inhibitors, phototherapy, retinoids (including the recent alitretinoin), and immunosuppressants. Targeted therapies are lacking. application/pdf https://sonar.ch/global/documents/298326 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.iac.2016.08.014 info:eu-repo/semantics/altIdentifier/pmid/27886903 info:eu-repo/semantics/openAccess Immunology and allergy clinics of North America. - 2017 Allergen Contact Dermatitis Patch T cell Work related Allergens Dermatitis, Allergic Contact Dermatitis, Irritant Diagnosis, Differential Humans Occupational Exposure Patch Tests Skin Allergic Contact Dermatitis. http://purl.org/coar/resource_type/c_6501