<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Poirel, Laurent</dc:creator>
  <dc:creator>Kieffer, Nicolas</dc:creator>
  <dc:creator>Nordmann, Patrice</dc:creator>
  <dc:date>2017-04-17</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">The plasmid-mediated mcr-1 gene encodes a phosphoethanolamine transferase  conferring resistance to polymyxins. The mcr-1 gene is associated with insertion  sequence ISApl1 (IS30 family). In-vitro mobilization assays demonstrated the  functionality of the composite transposon structure ISApl1-mcr-1-ISApl1. Transposition  generated a 2-bp duplication and occurred in AT-rich DNA regions. This is the first  report demonstrating the mobility of the mcr-1 gene by transposition.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/305498</dc:identifier>
  <dc:identifier>https://sonar.ch/documents/305498/files/nor_ivs.pdf</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1128/AAC.00127-17</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>License undefined</dc:rights>
  <dc:source>Antimicrobial Agents and Chemotherapy. - 2017, p. AAC.00127-17</dc:source>
  <dc:subject>info:eu-repo/classification/udc/57</dc:subject>
  <dc:title xmlns:ns1="xml" ns1:lang="en">In-vitro study of ISApl1-mediated mobilization of the colistin resistance gene mcr-1</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>