<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Vassella CC</dc:creator>
  <dc:creator>de Weck AL</dc:creator>
  <dc:creator>Stadler BM</dc:creator>
  <dc:date>1990</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">IgE fragments were detected by polyclonal and monoclonal anti-IgE antibodies using Western blot techniques and immunoassays. Other antibodies detected only intact IgE molecules. In the presence of IgE fragments, higher IgE levels were estimated, depending on the epitope specificity of the antibodies used in the IgE determination assays. IgE fragments have been found together with intact IgE in isolated material from different human sera and also from culture supernatant of an IgE-producing cell line. Our data demonstrate that IgE fragments may be assessed and represent a potential pitfall in diagnostic IgE determinations.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/31752</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1159/000235189</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/2276844</dc:relation>
  <dc:source>International archives of allergy and applied immunology. - 1990</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Antibodies, Anti-Idiotypic</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Blotting, Western</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Chromatography, Affinity</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Chromatography, High Pressure Liquid</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Electrophoresis, Polyacrylamide Gel</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Immunoglobulin E</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Immunoglobulin Fragments</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Multiple Myeloma</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Radioimmunoassay</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Reproducibility of Results</dc:subject>
  <dc:title xmlns:ns12="xml" ns12:lang="en">Influence of IgE fragments on IgE determination.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>