<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Müller M</dc:creator>
  <dc:creator>Haeberli A</dc:creator>
  <dc:date>1994</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Pure ethylenediaminetetraacetic acid tetrasodium salt (EDTA.Na4) in water showed a pH-dependent change of optical density detected in the ultraviolet region. The most important change was found between pH 4 and 8, corresponding to the deprotonation of the third ionizable group having a pK of 6.2. The absorbance change was reversible and depended on the addition/removal of only 1 proton equivalent. The presence of supramolecular aggregates was suggested by size-exclusion chromatography, dialysis and cryo-electronmicroscopy. The molecular weight of EDTA supramolecular aggregates was 10-15,000 and 8-14,000, as determined by gel chromatography and dialysis, respectively. Cryo-electronmicroscopy revealed structures of 2-4 nm in diameter.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/31852</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/0014-5793(94)80164-9</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/8119401</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>FEBS letters. - 1994</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Chromatography, Gel</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Dialysis</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Edetic Acid</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Hydrogen-Ion Concentration</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Microscopy, Electron</dc:subject>
  <dc:title xmlns:ns6="xml" ns6:lang="en">pH-dependent formation of ethylenediaminetetraacetic acid supramolecular aggregates.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>