Biermé P Nowak-Wegrzyn A Caubet JC 2017 PURPOSE OF REVIEW We focus on recent advances regarding the epidemiology, physiopathology, diagnosis and managements of non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs), particularly food protein-induced enterocolitis syndrome (FPIES). RECENT FINDINGS The first international FPIES diagnostic and management guidelines have been recently published. Although FPIES largely remains a diagnosis of exclusion, it may be more prevalent than previously thought. Ondansetron has emerged as a major tool for the treatment of FPIES acute reactions. Recent data also suggest an important role for innate immune cells in FPIES pathogenesis. SUMMARY Despite major advances in the diagnosis and management of non-IgE-GI-FAs, particularly FPIES, the lack of specific diagnostic tests and biomarkers to guide clinical management remains challenging. https://sonar.ch/global/documents/33982 eng info:eu-repo/semantics/altIdentifier/doi/10.1097/MOP.0000000000000554 info:eu-repo/semantics/altIdentifier/pmid/28937509 Current opinion in pediatrics. - 2017 Enterocolitis Food Hypersensitivity Humans Immunoglobulin E Syndrome Non-IgE-mediated gastrointestinal food allergies. http://purl.org/coar/resource_type/c_6501