<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Coste AT</dc:creator>
  <dc:creator>Kritikos A</dc:creator>
  <dc:creator>Li J</dc:creator>
  <dc:creator>Khanna N</dc:creator>
  <dc:creator>Goldenberger D</dc:creator>
  <dc:creator>Garzoni C</dc:creator>
  <dc:creator>Zehnder C</dc:creator>
  <dc:creator>Boggian K</dc:creator>
  <dc:creator>Neofytos D</dc:creator>
  <dc:creator>Riat A</dc:creator>
  <dc:creator>Bachmann D</dc:creator>
  <dc:creator>Sanglard D</dc:creator>
  <dc:creator>Lamoth F</dc:creator>
  <dc:date>2020</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In this study, we report the emergence of FKS-mutant Candida albicans/glabrata in Switzerland and provide the microbiological and clinical characteristics of 9 candidemic episodes. All patients were previously exposed to echinocandins (median 26 days; range 15-77). Five patients received initial echinocandin therapy with persistent candidemia in 4 of them. Overall mortality was 33%.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/34467</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1007/s15010-020-01475-8</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/32661647</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Infection. - 2020</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Microbiology (medical)</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Infectious Diseases</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">General Medicine</dc:subject>
  <dc:title xmlns:ns4="xml" ns4:lang="en">Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
