Zakharov P Völker A Buck A Weber B Scheffold F 2006 We have analyzed the image formation and dynamic properties in laser speckle imaging (LSI) both experimentally and with Monte Carlo simulation. We show for the case of a liquid inclusion that the spatial resolution and the signal itself are both significantly affected by scattering from the turbid environment. Multiple scattering leads to blurring of the dynamic inhomogeneity as detected by LSI. The presence of a nonfluctuating component of scattered light results in the significant increase in the measured image contrast and complicates the estimation of the relaxation time. We present a refined processing scheme that allows a correct estimation of the relaxation time from LSI data. application/pdf https://sonar.ch/global/documents/34973 eng info:eu-repo/semantics/altIdentifier/doi/10.1364/ol.31.003465 info:eu-repo/semantics/altIdentifier/pmid/17099751 info:eu-repo/semantics/openAccess Optics letters. - 2006 Computer Simulation Diagnostic Imaging Image Interpretation, Computer-Assisted Lasers Light Models, Chemical Nephelometry and Turbidimetry Refractometry Scattering, Radiation Quantitative modeling of laser speckle imaging. http://purl.org/coar/resource_type/c_6501