<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Hotz MA</dc:creator>
  <dc:creator>Harris FP</dc:creator>
  <dc:creator>Probst R</dc:creator>
  <dc:date>1994</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Ototoxic drugs, such as aminoglycosides, affect outer hair cell integrity in the inner ear. Transiently evoked otoacoustic emission (TEOAE) characteristics are related to outer hair cell function and can be expected to reflect the influence of ototoxic agents. Transiently evoked otoacoustic emissions were measured during amikacin sulfate therapy in nine patients. The duration of treatment for individual patients ranged from 9 to 33 days. A reversible decrease of overall TEOAE level, occurring after a treatment period longer than 16 days, was found in the majority of patients. The monitoring of TEOAEs is proposed as a method for early identification and, as a result, prevention of aminoglycoside-induced ototoxicity.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/36832</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1288/00005537-199409000-00014</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/8072361</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>The Laryngoscope. - 1994</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Adolescent</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Aged</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Amikacin</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Audiometry, Pure-Tone</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Auditory Perception</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Auditory Threshold</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Cochlea</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Evoked Potentials, Auditory</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Hair Cells, Auditory, Outer</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Hearing</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Hearing Disorders</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Leukemia</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Middle Aged</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Monitoring, Physiologic</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Reproducibility of Results</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Time Factors</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Tinnitus</dc:subject>
  <dc:title xmlns:ns22="xml" ns22:lang="en">Otoacoustic emissions: an approach for monitoring aminoglycoside-induced ototoxicity.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>