Weber WP Morrow M Boniface J Pusic A Montagna G Kappos EA Ritter M Haug M Kurzeder C Saccilotto R Schulz A Benson J Fitzal F Matrai Z Shaw J Peeters MV Potter S Heil J 2020 The aims of the Oncoplastic Breast Consortium initiative were to identify important knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction, and to recommend appropriate research strategies to address these gaps. A total of 212 surgeons and 26 patient advocates from 55 countries prioritised the 15 most important knowledge gaps from a list of 38 in two electronic Delphi rounds. An interdisciplinary panel of the Oncoplastic Breast Consortium consisting of 63 stakeholders from 20 countries obtained consensus during an in-person meeting to select seven of these 15 knowledge gaps as research priorities. Three key recommendations emerged from the meeting. First, the effect of oncoplastic breast-conserving surgery on quality of life and the optimal type and timing of reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiotherapy should be addressed by prospective cohort studies at an international level. Second, the role of adjunctive mesh and the positioning of implants during implant-based breast reconstruction should ideally be investigated by randomised controlled trials of pragmatic design. Finally, the BREAST-Q questionnaire is a suitable tool to assess primary outcomes in these studies, but other metrics to measure patient-reported outcomes should be systematically evaluated and quality indicators of surgical morbidity should be further assessed. application/pdf https://sonar.ch/global/documents/40026 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/S1470-2045(20)30084-X info:eu-repo/semantics/altIdentifier/pmid/32758475 info:eu-repo/semantics/openAccess The Lancet. Oncology. - 2020 Breast Neoplasms Female Humans Mammaplasty Knowledge gaps in oncoplastic breast surgery. http://purl.org/coar/resource_type/c_6501