<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Liu Y</dc:creator>
  <dc:creator>Manesso E</dc:creator>
  <dc:creator>Gunawan R</dc:creator>
  <dc:date>2015</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">UNLABELLED
Here, we present REDEMPTION ( RE: duced D: imension E: nsemble M: odeling and P: arameter estima TION: ), a toolbox for parameter estimation and ensemble modeling of ordinary differential equations (ODEs) using time-series data. For models with more reactions than measured species, a common scenario in biological modeling, the parameter estimation is formulated as a nested optimization problem based on incremental parameter estimation strategy. REDEMPTION also includes a tool for the identification of an ensemble of parameter combinations that provide satisfactory goodness-of-fit to the data. The functionalities of REDEMPTION are accessible through a MATLAB user interface (UI), as well as through programming script. For computational speed-up, REDEMPTION provides a numerical parallelization option using MATLAB Parallel Computing toolbox.


AVAILABILITY AND IMPLEMENTATION
REDEMPTION can be downloaded from http://www.cabsel.ethz.ch/tools/redemption.


CONTACT
rudi.gunawan@chem.ethz.ch.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/40893</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1093/bioinformatics/btv365</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/26076722</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Bioinformatics (Oxford, England). - 2015</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Algorithms</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Models, Biological</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Software</dc:subject>
  <dc:title xmlns:ns4="xml" ns4:lang="en">REDEMPTION: reduced dimension ensemble modeling and parameter estimation.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
